Abstract
The case of an extramedullary plasmacytoma of the bilateral paranasal sinuses is reported.
A 61 year-old male was referred to our clinic complaining of right nasal bleeding. A CT scan and MRI revealed a tumor in the right ethmoidal sinus. The histopathological diagnosis was an IgA-type plasmacytoma. Following VAD chemotherapy (a combination therapy consisting of vincristine, adriamycin and dexamethasone) and radiation, the tumor disappeared rapidly. Five months later, the tumor recurred in the left maxillary sinus. A M-2 chemotherapy protocol (a combination of vincristine, cyclophosphamide, ranimustine, melphalan, and prednisolone) and radiation reduced the tumor size significantly. Both the VAD chemotherapy and the M-2 chemotherapy protocol were effective against this tumor. No recurrence or progression to a multiple myeloma has been noted for the past five years.
