Abstract
We report an obscure case for diagnosis due to simultaneous appearance of varied, serious symptoms of fever, jaundice, skin erythema, increased monocytes, hepatic and respiratory failure, and disseminated intravascular coagulation syndrome (DIC). The case history showed self-medication of diaminodiphenyl sulfone (DDS) in addition to known prescribed medication, and the case was diagnosed as DDS syndrome. Clinical pharmacists can play an important role in diagnosis and treatment because of their complex knowledge of interactions and side effects of a broad range of different drugs. For this reason, clinical pharmacists have been invited to participate in daily ICU conferences at Hiroshima University Hospital since 1998. We describe a case with DDS syndrome in which the contribution of the clinical pharmacist was vital to patient diagnosis and treatment. The diagnosis of drug-induced side effects was determined based on data presented by the clinical pharmacist.
