Abstract
We conducted a retrospective review of 2,641 cases of breast cancer treated surgically between April 2000 and March 2007 for which both preoperative mammography (MLO and CC view) and sonography data were available. Among these cancers (overall BC), 202 (7.6%) were detected only by sonography, and were negative by mammography (US-BC). Analysis of age distribution showed that US-BC detected cancers more frequently in women in their thirties (11.9% vs 7.5%) and forties (39.1% vs 26.2%). Non-invasive ductal carcinoma was predominant among the US-BC cases, compared with overall BC (32.7% vs 12.4%). Invasive ductal carcinomas less than 1cm in diameter were more prevalent among US-BC cases than among overall BC (32.8% vs 17.3%). DCIS and invasive ductal carcinomas less than 1cm in diameter comprised 88.9% of US-BC cases, compared with 60% of overall BC. In conclusion, we suggest that sonography should carried out in addition to mammography in order to detect DCIS and early-stage cancer, particularly in women under 50 years old and those with dense breast tissue.
