Abstract
Conformation and intermolecular interaction of Laminin-1 (LN-1) in pseudophysiological solutions were investigated by dynamic light scattering technique. We found that hydrodynamic radius of LN-l was 20.0 nm, which was smaller than that expected from a cruci-form of LN-1. The intermolecular interaction between molecules was estimated as a function of magnesium concentration, showing that an attractive force increased as increase in Mg concentration.