Abstract
In order to study effects of smoking on electrocardiographs, Holter Electrocardiographic examination concurrent with tobacco smorking were performed in 28 smokers, average age 52 years old, with no abnormal findings in usual resting ECGs.. Positive inchemic STT changes, iscluding deep T wave inversion and prominent arrhythmias were identified by the Maruquette 8200 System Analysis. These positive changes generally appeared 4-5 minutes after commencing smorking. Thirteen out of 28 (43%) of the subjects had positive findings. The positive group also had significantly elevated values for the Coronary Atherogenic Index : (TC/ HLD-C × Apo B/ Apo A-I), compared to the negative group.
After premedication with Ca-antagonists, ischemic STT changes did not appear. These ischemic STT changes which did not always appear at smoking, had a tendency to show when smoking occurred during driving, in cold environment, after micturition at midnight, upon waking in the morning, probably at times of low levels of threshold.
