Abstract
A 50-year-old woman was admitted to our hospital because of epigastralgia. Upper gastrointestinal endoscopy revealed the giant protruding tumor with ulceration and normal gastric mucosa, like the submucosal tumor, in the upper body of the stomach. A biopsy specimen was histologically proved to be poorly differentiated type carcinoma, showing partially endocrine cell morphology. Enhanced abdominal CT scan revealed a tumor with a diameter of about ６ cm showing a lump of the stomach, pancreatic tail and hilum of spleen. Total gastrectomy and combined resection of the distal pancreas and spleen was conducted. The tumor was histologically diagnosed as poorly differentiated neuroendocrine carcinoma of the stomach with invasion to pancreas.
We report a case of neuroendocrine carcinoma of the stomach with invasion to the pancreas which is comparatively rare, together with a review of the literature.
