Abstract
A 56-year-old woman was admitted to our hospital with a mass in her left breast and hard lymph nodes in her left axillary, which were both diagnosed as the malignancy by fine-needle aspiration cytology. It was diagnosed as invasive micropapillary carcinoma (IMPC) by core needle biopsy. Immunohistochemical investigations showed positive for estrogen and progesterone receptors, negative for Her2 and 35.2% of Ki67. The patient was treated with pre-operative chemotherapy using EC 4 cycles and weekly PTX 12 cycles. After administration, the CT scan showed complete remission of the breast tumor and axillary swollen lymph nodes. A breast-conserving surgery with axillary dissection was performed. The pathological findings after the operation showed that the resected specimen was principally scar-like fibrosis nest, which was esimated at the cancer cells necrosis and the extirpated lymph nodes were no cancer cells. After post-operative radiotherapy, the patient has been well without recurrence for 3 years and 7 months under treatment with aromatase inhibitor. The patient of IMPC was usually performed mastectomy owing to a clinically aggressive carcinoma and poor prognosis. This report suggests the breast-conserving therapy with the following endocrine therapy is a feasible treatment for the effective pre-operative chemotherapy and ER positive IMPC case.
