Abstract
Xanthogranulomatous cholecystitis (XGC) is a destructine inflammatory disease of the gallbladder, which can rarely involve adjacent organ and mimic advanced gallbladder carcinoma. A 77-year-old man was added to our hospital complaining of epigastralgia. Abdominal ultrasonography and computed tomography showed gallstone, segmental thickening of the gallbladder wall and a heterogenous mass with low density areas located in the adjacent liver. A serum CA19-9 level was markedly increased and FDG-PET imaging showed definite uptake at the gallbladder lesion. Serological and imaging data were indicative of gallbladder carcinoma and we performed an extended cholecystectomy. Histopathological examination revealed a XGC with no evidence of malignancy. XGC should be kept in mind as a differential diagnosis of gallbladder carcinoma because of high level of serum CA19-9 and abnormal accumulation of FDG-PET.
