Abstract
We retrospectively investigated differences of characteristics between superficial Barrett adenocarcinoma and squamous cell carcinoma in the esophagogastric junction. Lower esophagectomy combined with proximal gastrectomy was performed in 11 superficial Barrett adenocarcinomas and 7 superficial squamous cell carcinomas in the esophagogastric junction. In cases with superficial Barrett adenocarcinoma, heartburn feeling, esophageal hiatal hernia, hypertension, and diabetes mellitus were frequently observed. Histologic node metastasis was observed in 3 cases with superficial Barrett adenocarcinoma. In cases with superficial squamous cell carcinoma, chronic pulmonary diseases and other primary cancers were frequently observed. All patients were given PPI after surgery, and there was no difference regarding heartburn feeling and endoscopic findings evaluated by the Los Angeles classification between cases with Barrett adenocarcinoma and squamous cell carcinoma. Furthermore, no adenocarcinoma was newly detected after surgery. In conclusion, there were several differences between superficial Barrett adenocarcinoma and squamous cell carcinoma in the esophagogastric junction, and these patients should be treated with attention to these differences. because node metastasis was observed in 27.3% of superficial Barrett adenocarcinoma, we should investigate node metastasis carefully before surgery and endoscopic treatment.
