Abstract
Herein, we report two thyroid tumors that had been misdiagnosed by fine needle aspiration cytology (FNA); operative rapid pathologic diagnosis confirmed that were actually hyalinizing trabecular tumors.
Case 1: The patient was diagnosed with a malignant tumor in the right lobe of her thyroid by FNA based on the existence of nuclear grooves and intranuclear inclusion bodies before the operation. However, after total thyroidectomy, operative rapid pathologic diagnosis revealed that the tumor was actually a hyalinizing trabecular tumor, and thus she was not required to undergo cervical lymph node dissection. Histological findings also confirmed that the lesion was a hyalinizing trabecular tumor as cell membranes stained positive for MIB-1. Two years have passed without any recurrence.
Case 2: The patient was diagnosed with a malignant tumor in the right lobe of her thyroid by FNA based on the existence of intranuclear inclusion bodies. However, after total thyroidectomy, operative rapid pathologic diagnosis revealed that the tumor was a hyalinizing trabecular tumor, and thus, like Case 1, the patient did not require cervical lymph node dissection. Histological findings also confirmed that the lesion was a hyalinizing trabecular tumor based on cell membrane positivity for MIB-1. Three months have passed without recurrence.
