Abstract
A 57-year-old woman was admitted due to diagnosis GBC. Enhanced computed tomography showed a wall thickening of the gallbladder and an unclear borderline between gallbladder and adjacent liver and colon. Positron Emission Tomography (PET) showed an abnormal accumulation of FDG in the region. Surgical operation was performed under a diagnosis of GBC with invasion to hepatic bed and colon. No malignant sign was found by intraoperative frozen examination, then extended cholecystectomy and partial resection of the colon was undertaken. Extra hepatic bile duct and lymph node resection were never undertaken. The result of pathologic diagnosis from permanent preparation was a xanthogranulomatous cholecystitis (XGC). XGC is one type of subacute cholecystitis showing similar examination findings to gallbladder cancer (GBC). Accumulating of FDG was often seen in XGC. It is often difficult to differentiate XGC from GBC preoperatively, so that too much invasive operation was performed. When we diagnosed GBC preoperatively, we consider that it is important to set a high value on intraoperative findings and a frozen examination to avoid unnecessary surgical stress.
