Abstract
Goblet cell carcinoid (GCC) of the appendix is rarely diagnosed preoperatively and mostly diagnosed after appendectomy. Although additional resection including lymph node dissection is considered in patients with a potential risk of recurrence, there has been little data about the incidence of lymph node metastases. Here, we present a case report on GCC of the appendix and a review of the published literatures in Japan. An 80-year-old man presented at our hospital with abdominal pain. He was diagnosed with acute appendicitis and underwent emergency laparoscopic appendectomy. Histopathological examination revealed a GCC of the appendix, with subserosal invasion. He underwent ileocecectomy with D3 lymph node dissection following appendectomy because lymph node metastasis was highly suspected. As a result, histopathological findings showed neither residual tumor nor lymph node metastases. The review of the Japanese literatures indicated that the deeper the extent of tumor infiltration, the greater the possibility of lymph node metastases, to be 12.9% in cases with subserosal invasion. Hence, we propose that the depth of tumor infiltration is a novel criteria of additional resection and it would be preferable to add the precise lymph node dissection in patients with subserosal invasion or more.
