Abstract
A 63-year-old man was admitted to our hospital for treatment of a huge abdominal tumor. Computed tomography and magnetic resonance imaging of the abdomen revealed a 20-cm heterogeneous mass in the retroperitoneum of the right upper quadrant. With a diagnosis of retroperitoneal tumor, the patient underwent laparotomy. Because the tumor invaded or was adherent to the duodenum, pancreas head, colon, right kidney, and inferior vena cava, we performed pancreaticoduodenectomy, right hemicolectomy, right nephrectomy and partial resection of the inferior vena cava for complete resection of the tumor. The tumor was histopathologically diagnosed as retroperitoneal leiomyosarcoma. Because the patient developed local recurrence 17 months after surgery, he received systemic chemotherapy using Doxorubicin and Ifosfamide. However, the patient died 28 months after surgery due to wide-spread recurrence of leiomyosarcoma.