A Case of Multiple Intraabdominal Desmoid Tumors that Developed in Familial Adenomatous Polyposis after Colectomy

Abstract

Desmoids are very rare tumors in the general population but occur frequently in FAP patients. The patient was a 38-year-old man who underwent a prophylactic total colectomy and ileostomy for familial adenomatous polyposis (FAP) 4 years ago. Three years ago, follow-up CT scan revealed multiple intraabdominal and intrapelvic tumors. At surgery, intrapelvic tumor invading around tissues and intraabdominal tumor arising from the mesentery of the small intestine were found, and any tumors could not be completely excised. The patient was diagnosed with desmoid tumor, Stage Ⅱ according to the Churchʼs classification. We then performed sulindac therapy for the residual desmoid tumors after surgery. We added tamoxifen, because there was slight growth of the residual desmoid tumors for 12 months after sulindac therapy. After tamoxifen added, sporadic desmoid tumors demonstrated cessation of growth and have being well under control.