2018 Volume 43 Issue 2 Pages 216-221
An 82-year-old woman was admitted to evaluate aortic valve stenosis and anemia. Sigmoid colon cancer was pointed out by colonoscopy. A laparoscopic sigmoid colectomy was performed as definitive treatment. Pathological findings revealed sigmoid colon cancer composed of moderately differentiated tubular adenocarcinoma that was surrounded by endocrine cell carcinoma. The endocrine cell carcinoma accounted for 90 percent of the total components whereas adenocarcinoma component accounted for 10 percent. Finally this tumor was diagnosed as endocrine cell carcinoma. In endocrine cell carcinoma component, the expression of p53 was positive, and Ki-67 index was 80-90%, which was higher than in adenocarcinoma component. In general, patients with colorectal tubular adenocarcinoma involved with endocrine cell carcinoma have poor prognosis. Although it has passed 48 months since she underwent the surgery, she is still alive with no recurrence.
