2018 Volume 43 Issue 6 Pages 1078-1083
A male of fifty with abdominal pain and vomiting was admitted to our hospital. Physical examination revealed tenderness in the right lower abdomen. Contrast-enhanced abdominal computed tomography showed increased wall thickness of the appendix, with a high-density area surrounding the appendix. The patient was diagnosed with acute appendicitis and underwent emergency surgery. Histological assessment of the root of the resected appendix revealed a component with signet ring cell carcinoma morphology that was positive for neuroendocrine markers by immunohistochemical staining, which led to the diagnosis of goblet cell carcinoid (GCC) of the appendix. GCC cells were found to infiltrate the surrounding serosa and at the resected margin. An additional laparoscopic ileocecal resection with D3 dissection was performed. The frequency of GCC is 0.05％ among all appendectomy cases, and half of the patients with GCC are diagnosed as acute appendicitis preoperatively. We herein report our experience in a patient with acute appendicitis who underwent additional laparoscopic surgery after appendectomy for GCC and present review of the literature.
