2019 Volume 44 Issue 1 Pages 82-89
A 71-year-old woman underwent treatment at our hospital for chronic hepatitis B. An annual ultrasonography revealed a 15-mm diameter hypoechoic tumor situated in segment 7 of the liver. Abdominal dynamic computerized tomography revealed early enhancement and washout, and prolonged enhancement in a part of the tumor. Abdominal EOB-MRI showed the tumor as a low-signal intensity in the hepatobiliary phase; therefore, the tumor was diagnosed as a hepatocellular carcinoma. Resection of segment 7 of the liver was performed. The tumor did not contain any areas of typical hepatocellular carcinoma (HCC) or cholangiocarcinoma (ChC). We made the diagnosis of combined hepatocellular carcinoma (CHC), CHC subtypes with stem cell features (WHO, 2010), most probably. CHC subtypes with stem cell features is a second type of CHC that was added in 2010.
We report a case of CHC without any tumor areas showing the typical features of HCC or ChC.
