2019 Volume 44 Issue 2 Pages 176-181
Radical resection for esophageal cancer is a highly invasive operation, and patients often develop serious postoperative complications, such as arrhythmias; therefore, perioperative care for such complications is particularly important. In our case series, among 141 patients who underwent radical resection for esophageal cancer, 19 developed tachyarrhythmias. The rate of occurrence of tachyarrhythmias was higher in patients with electrocardiographic abnormalities or circulatory diseases before the operation (p = 0.0001, 0.006). Landiolol hydrochloride, a short-acting β1 selective blocker, was administered in 12 of the 19 patients, and sinus rhythm was immediately restored on the electrocardiogram in 10 of the 12 patients. Neither reduction of the blood pressure nor deterioration of the respiratory status was observed. For controlling perioperative tachyarrhythmias in patients with esophageal cancer, we consider landiolol hydrochloride as a safe and effective drug, and its use is expected to increase.
