2020 Volume 45 Issue 1 Pages 68-73
A 76-year-old woman visited our hospital with abdominal pain, diarrhea and abdominal distension, and was subsequently diagnosed as having a large type 2 tumor of the rectum (RSRa). A second-look operation was scheduled after chemotherapy to ascertain expected tumor shrinkage because the huge tumor was occupying whole pelvis. After transverse colostomy, six courses of mFOLFOX6 plus bevacizumab therapy were administered. Since subsequent examinations revealed a significant decrease in the size of the primary lesion and disappearance of swollen lymph nodes, high anterior resection was performed curatively. The pathological examination revealed that there were no residual cancer cells, neither at the primary lesion nor the lymph nodes, and thus pathological CR was achieved.