Pancreatic Xanthogranuloma with High Accumulation in Fluorodeoxyglucose-Positron Emission Tomography

Abstract

An 83-year-old man presented our hospital with enlarging cystic lesion in the pancreatic head. The lesion had a solid component, which was found to be irregularly enhancing by dynamic computed tomography. Positron emission tomography revealed high uptake of fluorodeoxyglucose in the lesion. No malignant cells were found in pancreatic juice or biliary cytology, but the lesion was considered as an intraductal papillary mucinous carcinoma because of the progressive increase in size and the radiological findings. Pancreatoduodenectomy combined with portal vein resection was performed. Histopathological examination showed intraductal papillary mucinous adenoma with adjacent granulomas. No atypical cells suggestive of malignancy were found. The histopathological diagnosis was a xanthogranuloma present concurrently with an intraductal papillary mucinous adenoma.