2021 Volume 46 Issue 5 Pages 582-587
A 74-year-old woman was referred to our hospital with anemia and a submucosal tumor in the duodenal bulb showing intraluminal growth, with ulceration at the top. Surgery was planned, and partial resection of the duodenal bulb was performed by laparoscopy and endoscopy cooperative surgery (LECS). Submucosal layer dissection was performed to the maximum extent possible, the deepest part was perforated by endoscopy and laparoscopic full-thickness resection was performed with the least margin. The defect in the duodenal bulb was closed with Albert-Lembert sutures, using an omental patch. The tumor, which measured 5 × 3 cm in size, was successfully extracted through the 2-cm wall defect. No postoperative stenosis was observed. The histopathological diagnosis was Brunner’s gland hyperplasia. We report a case in which LECS was useful for resection of a giant duodenal Brunner’s gland hyperplasia with bleeding.