2024 Volume 49 Issue 1 Pages 29-34
An 82-year-old man with a splenic tumor was admitted to our hospital. Enhanced contrasted CT and FDG-PET/CT showed a well-defined tumor measuring 13 cm and an FDG-avid spleen. Additionally, laboratory data revealed that the serum IL-2 receptor was elevated. Based on these findings, malignant lymphoma was suspected. Therefore, the patient underwent laparoscopic splenectomy. Histopathologically, the resected specimen was diagnosed with hairy cell leukemia (HCL) due to the presence of immunohistological markers. Generally, HCL clinically presents as pancytopenia and splenomegaly.
This case served as an important reminder to consider HCL in the investigation of all possible causes of splenic tumors.