A Case Report of Metachronous Pancreatic Metastasis Occurring Seven Yearsafter Colorectal Cancer Surgery

Abstract

A 70-year-old woman was referred to our hospital for treatment of rectal cancer and metastatic lung tumor by her primary care physician and underwent colostomy, chemotherapy, and posterior pelvic exenteration, subsequently. A year later, she underwent thoracoscopic bilateral pneumonectomy for lung metastasis and tumor resection for local recurrence in the pelvic cavity. She continued chemotherapy and underwent a CT imaging at the age of 76 years. The CT findings revealed the presence of an irregular lesion in the pancreatic body and tail. Consequently, she was diagnosed with primary pancreatic cancer and underwent resection of the pancreatic body and tail. Histopathological findings revealed a white solid mass located in the pancreatic body and tail with coagulative necrosis in the center of the mass. Immunostaining confirmed that the lesion was negative for cytokeratin 7 and positive for cytokeratin 12. Consequently, the patient was diagnosed with pancreatic metastasis of colorectal cancer. She was discharged without any postoperative complications and currently has demonstrated no signs of recurrence at 4 months after surgery. Pancreatic metastasis of colorectal cancer is rare, and we report this case with consideration based on references.