2024 Volume 49 Issue 4 Pages 411-416
A 76-year-old man underwent laparoscopic resection of the sigmoid colon and partial hepatectomy (S2) for sigmoid colon cancer and comorbid liver metastasis (S2). Postoperative adjuvant chemotherapy (four courses of XELOX + four courses of Xeloda) was administered. A year after surgery, abdominal EOB-MRI revealed new tumors in S2 and S6 of the liver. The patient was diagnosed preoperatively with multiple metachronous liver metastases of colorectal cancer (S2, S6) and could undergo laparoscopic partial hepatectomy (S2, S6), although the patient had undergone a repeat hepatectomy. Pathological findings revealed the S2 lesion to be a metastatic lesion from colorectal cancer, whereas the S6 lesion was a well-differentiated hepatocellular carcinoma. Although the differential diagnosis of liver tumors is often difficult, especially in the case of resected colorectal cancer, careful preoperative evaluation is important, considering the possibility of overlapping hepatocellular carcinoma.