Abstract
It is well known that growth hormone (GH) is anabolic agent which effects on the metabolism of lipid, carbohydrate, and protein1, 2) . Especially GH stimulates protein metabolism and accumulates positive nitrogen balance. Although nitogen sparing effect of GH has been examined for healthy subjects, burned patients and the patients with elective surgery3, 4, 5) , there are only a few papers described for the effect on septic condition6, 7) .
In order to estimate the effect of recombinant human growth hormone (HGH) on protein metabolism in septic condition, two experimental studies were designed using sepsis models induced by cecal ligation and induced by administration of endotoxin to rats.
