Abstract
As a part of study on primer used for dentin adhesion, seven kinds of methacrylate monomers shown in Fig.1, having a pyrrolidone ring or acetamide group as a hydrophilic moiety, were prepared and studied for their hydrophilicity by measuring the partition coefficient in octhanol/water, their cytotoxicity by the cell culture method and their effect on adhesion between the MMA/PMMA-TBBO resin and dentin.The partition coefficient of the monomers was 2.6〜20.5, which was similar to the value corresponding to 2-hydroxyethyl methacrylate(HEMA)and MMA.The cytotoxicity of the monomers increased in the following order:(MMA)<MEP<MPP, (HEMA)<MMEA<MBP<MEMP<MPeP<MMPP<MEA.MEP was less cytotoxic than HEMA.Some monomers, when used as a primer, were considerably effective in improving the bond strength between dentin and the resin.Maximum bond strength of 18.2MPa was obtained in an aqueous MPP primer in comparison with control value of 9.4MPa.There was some correlation between the bond strength and partition coefficient of the monomer used for pimer and that monomer with a partition coefficient of 5〜9 was suitable for the adhesion.
