Abstract
We examined the effects of extracts and filtrates on cell viability after gyration of six types of spherical restorative materials on a titanium plate.The extracts obtained with titanium coupled with Type 3 gold alloy, gold-silver-palladium alloy, titanium and composite resin did not affect the cell viability, while the extracts obtained with titanium coupled with cobalt-chromium alloy or nickel-chromium alloy suppressed the cell viability with increased specimen weight, or gyration speed, or extraction period.The extracts and filtrates had similar effects on cell viability.Cell viability decreased by the extraction in serum-containing MEM.The present method of obtaining extracts from restorative materials coupled with titanium might be an approach to express in vitro cytotoxicity of dental materials which are occluded with others in the mouth.