The Journal of the Japanese Society for Dental Materials and Devices
Online ISSN : 2188-4188
Print ISSN : 0286-5858
ISSN-L : 0286-5858
Original Article
Studies on Ni-Ta Alloys : (Part 3)The Biocompatibility of Ni-Ta Alloys and Human Fibroblasts
Masayuki KAGAMasaaki ONOKIYoshinobu NODASAKAIkuya WATANABEKiyoshi OIKAWAMamoru OTA
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1984 Volume 3 Issue 2 Pages 191-198

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Abstract
It has been reported that Ni-Ta alloys with compositions from Ni-20wt% Ta to Ni-30wt% Ta have good and sufficient mechanical properties as dental casting alloys, when comparing with cast base metal alloys, which are commercially available.The usefulness of these alloys was proved as dental casting alloys and in clinical applications.The biocompatibility of Ni-Ta alloys and human cultuyed fibloblasts were studied by tissue culture to determine the toxicity.The morphology of cultuyed fibroblast cells in the neighbourhood of metal specimens was observed and cell numbers were counted to determine the biocompatibility of the metals and the fibroblasts.The fibroblast cells grown with Ni-20wt% Ta and Ni-30wt% Ta specimens were similar to the control, revealing a good biocompatibility.These cultured fibroblast cells were arranged closely and normally around these alloy specimens.The fibroblasts grown with Ni metal showed changes in shape and disintegration, indicating cell damage.As a conclusion, alloys with compositions from Ni-20wt% Ta to Ni-30wt% Ta can be considered useful dental-and bio-materials.
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© 1984 The Japanese Society for Dental Materials and Devices
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