Abstract
The cytotoxic effects of pure metals on L-929 mouse fibroblasts were examined using extracts obtained by dynamic extraction of Cu, Al, Ti, V, Cr, Mo, Mn, Fe, Co and Ni. The order of cytotoxicity expressed in ppm was Cr>V>Co>Fe>Mn>Cu>Ni>>Mo. On the other hand, the order in mM was Cr>Co>V>Fe>Mn>Cu>Ni>>Mo. Al and Ti showed no cytotoxicity. Thus, the cytotoxicity of pure metals was dependent on their concentration and the chemical state in the extracts.
