Abstract
The objective of this study was to compare the neuropsychological findings between patients with amygdalo-hippocampal and lateral temporal lobe seizure.
Thirty-nine patients undergone epilepsy surgery for intractable seizures were estimated neuropsychological findings composed of Wechsler adult intelligence scale-revised, Minnesota multiphasic personality inventory, Wechsler memory scale-revised, verbal paired-associates learning test, story recall test, Benton's visual retention test, Rey-Osterrieth's complex figure test, Kana pick-out test, Japanese Raven's colored progressive matrices, and Japanese western aphasia battery.
There were twenty-eight patients with amygdalo-hippocampal seizure whose mean age at seizure onset was 13.8 years and mean age at surgery was 36.0 years. In these patients, seven patients showed psychiatric manifestations including delusion of reference and persecution. There were eleven patients with lateral temporal lobe seizure whose mean age at seizure onset was 13.6 years and the age at surgery was 29.2 years. There were more oversights in Kana pick-out test in patients with amygdalo-hippocampal seizure than in patients with lateral temporal lobe seizure (p<0.05). Discussion: Kana pick-out test reflects the function of orbito-frontal lobe, which suggests that patients with amygdalo-hippocampal seizure might have frontal lobe dysfunctions than patients with lateral temporal lobe seizure.
