Abstract
We conducted a questionnaire survey on the prevention against adverse effects during ACTH therapy. A questionnaire was sent to 113 institutes where the members of the board of counselors of the Japanese Society of Child Neurology are working. The replies from 51 institutes were analyzed. Tapering-off of ACTH was performed in 42 institutes. Tapering-off of ACTH was considered to be necessary in 35 institutes. The most common reason for its necessity was the concern for endocrinological problems. The precaution against infection was taken in 34 institutes. The correction of hypokalemia was made in 19 institutes. The evaluation of brain shrinkage was done in 46 institutes. Our study revealed a wide variety of prevention against adverse effect of ACTH. The standardization will be necessary in order to perform ACTH therapy more appropriately.
