2009 Volume 27 Issue 1 Pages 12-21
An open-label multi-center study was conducted to evaluate the effectiveness of gabapentin between September 2006 to February 2008. The study subjects consisted of 303 patients with various epilepsy and seizure types. More than 50% seizure reduction was obtained in 49 cases (16.2%). This result was almost compatible with those of phase III and long-term trial studies in Japan. The most common adverse effects were sleepiness and dizziness of slight degree, indicating a high tolerability. However, there were some cases with appearance/worsening of myoclonus and status epilepticus.