Journal of the Japan Epilepsy Society
Online ISSN : 1347-5509
Print ISSN : 0912-0890
ISSN-L : 0912-0890
A Case of Phenytoin Induced Lymphadenopathy
Tohshin Go
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1998 Volume 16 Issue 3 Pages 193-196

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Abstract
I am reporting on a boy with phenytoin induced lymphadenopathy. The patient showed right frontal spikes on his EEG and was diagnosed as having localizationrelated epilepsy. He became seizure-free after he began taking phenytoin. However, nine months after he started taking the phenytoin, he developed a fever and a rash, and his bilateral cervical lymph nodes became tender and swollon.Laboratory examination showed neutrophilia and a high value of C reactive protein. He became symptom free soon after the phenytoin was withdrawn and no relapse has been observed for 5 months. Lymphadenopathy induced by phenytoin should be carefully differentiated from inflammatory lymphadenitis and lymphoma, which could be manifested later.
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