Abstract
Twenty two patients with intractable seizures in infancy, early childhood excluding West and Lennox-Gastaut syndrome were followed up 2 to 6 years after the onset.
1) Most of seizures started from the first year of life. The seizure frequency increased in the second and third year of life, and decreased in the fifth or sixth year of life.
2) According to ictal symptomalogy, these seizures were classified into four types; “convulsive status” (in 7 cases), “generalized tonic or tonic-clonic” type (in 9 cases), “atonic” type (in 2 cases) and “partial” type (in 4 cases).
3) Epileptic interictal EEG abnormalities were found in only 6 patients (27%).
4) Neurological complications (mental retardation, cerebral palsy etc.) were found in 15 patients (68%).
