Cholangiocellular Carcinoma Associated with Wilson's Disease

Abstract

We report a rare case of cholangiocellular carcinoma associated with Wilson's disease (WD). A 39-year-old man diagnosed with WD at age 11 and administrated a copper chelating agent was hospitalized for further examination and treatment at age 39 after a tumorous lesion 40 mm in diameter was found. A series of imaging tests and percutaneous needle biopsy indicated well-differentiated adenocarcinoma. Following percutaneous transhepatic portal embolization, he underwent right hepatic lobectomy and lymph node dissection. The definitive histopathological diagnosis was moderately-differentiated cholangiocellur carcinoma with tumor formation.