The Japanese Journal of Gastroenterological Surgery
Online ISSN : 1348-9372
Print ISSN : 0386-9768
ISSN-L : 0386-9768
CASE REPORT
Clostridium Difficile-associated Refractory Pouchitis: Report of Three Cases
Hitoshi OgawaKouhei FukushimaChikashi ShibataKoh MiuraSho HanedaKeiichi HayashiHideyuki SuzukiIwao SasakiKen-ichi TakahashiYuji Funayama
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Keywords: pouchitis, C. Difficile
JOURNAL FREE ACCESS

2010 Volume 43 Issue 3 Pages 270-276

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Abstract
Pouchitis-the most common complication of total proctocolectomy and anal ileal-pouch anastomosis for ulcerative colitis-is effectively treated in most patients by antibiotic ciprofloxacin or metronidazole therapy, In some cases, however, pouchitis is refractory to these antibiotics. We detected Clostridium difficile toxin A in the feces of three patients suffering from antibiotic-refractory pouchitis whose mucosal inflammation was ameliorated by oral vancomycin treatment. C. difficile should therefore be considered in antibiotic-refractory pouchitis, which requires appropriate medication.
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この記事はクリエイティブ・コモンズ [表示 - 非営利 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc/4.0/deed.ja
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