Abstract
We report a very rare case of multiple cancer and adenomas of Japanese schistosomiasis (JS) indicating colorectal carcinogenesis of JS infection. A 66-year-old man admitted for abdominal pain had lived in Yamanashi Prefecture, an area endemic for JS. He had suffered liver dysfunction at the age of 10 years diagnosed as JS infection. X-ray imaging showed several niveaus indicating mechanical obstruction. Following ileus-tube decompression, colon fiberscopy showed advanced double cancer and one adenoma of the sigmoid colon and another of the rectosigmoid colon. Biopsy showed many JS ova around the cancer and adenomas. We conducted anterior resection with lymph node dissection. Five days after surgery jaundice appeared and was treated conservatively. Liver biopsy showed many JS ova. Such cases of multiple tumor or liver dysfunction thought to be at high risk for colon and liver cancer should be stringently followed up via colon fiberscopy and ultrasound observation.
