Abstract
We report a case of small-intestinal sarcomatoid carcinoma in a 74-year-old man admitted with severe anemia. X-ray examination of the small intestine failed to show the lower ileum, and abdominal computed tomography (CT) showed lymph node swelling at the base of the mesenterium. A tumor of the small bowel was revealed 70 cm from the ileocecal junction, along with lymph node swelling around the mesenteric artery. A partial ileectomy was performed with tumor and mesenteric lymph node resection. On histological examination and immunohistochemical staining, pleomorphic/sarcomatoid carcinoma was diagnosed. The tumor cells showed positive reaction for epithelial markers AE1/AE3, CAM 5.2, and EMA, and the stromal marker vimentin. Staining for both CEA and squamous differentiation were negative. The patient died of multiple liver metastasis on post-operative day 40. Sarcomatoid carcinoma is a rare form of primitive carcinoma of the small intestine. This is the 22nd case reported in the literature to date.
