Abstract
Pancreatic carcinosarcoma is a rare pancreatic neoplasmic variant with a dismal prognosis. We report the case of a large tumor of the pancreatic body in abdominal ultrasonography (US). A 58-year-old man was found in abdominal contrast computed tomography (CT) to have a 5cm low density mass at the pancreatic body. Based on a diagnosis of pancreatic cancer, we conducted distal-pancreatectomy from which the pathological specimen showed pancreatic carcinosarcoma involving invasive ductal adenocarcinoma and a sarcomatous area of short spindle cells. Sarcomatous cells stained immunohistochemically positive for a mesenchymal marker, yielding a diagnosis of pancreatic carcinosarcoma. Gemcitabine was administered in adjuvant chemotherapy. We found multidisciplinary treatment including surgery and chemotherapy effective in this case.