Abstract
We report an extremely rare case of solitary liver metastasis from papillary thyroid carcinoma. A 56-year-old woman referred for a lung-cancer screening-detected liver tumor. Her medical history included right thyroid lobectomy for papillary carcinoma 18 years earlier and total thyroidectomy for adenomatous goiter 2 years thereafter. Blood tests showed markedly-elevated preoperative serum thyroglobulin. Computed tomography (CT) showed a lateral hepatic tumor with a central scar and capsule-like structure. Contrast medium enhanced the lesion in the early phase, with washout in the late phase. Magnetic resonance imaging (MRI) showed lesions in the left seventh rib and first lumbar vertebra in the same phase as the liver tumor. Whole-body bone scintigraphy showed increased tracer uptake in the sixth thoracic vertebra and seventh rib, yielding a diagnosis of solitary liver tumor with multiple bone metastases. The liver tumor was suspected of being hepatocellular carcinoma and liver metastases from thyroid cancer. The liver tumor was resected concomitant to lateral segmentectomy with rib biopsy. Histopathologically, both lesions were papillary thyroid carcinoma metastases.
