A Case of Primary Squamous Cell Carcinoma of the Ileum That was Difficult to Diagnose

Abstract

A 90-year-old man was admitted for fever and abdominal pain. Lower gastrointestinal endoscopy and barium enema study showed a type 2 tumor at the ileocecum. Abdominal computed tomography releaved lymph node swelling around the tumor in addition to para-aortic lymph node swelling. We performed right colectomy and found that the tumor was in the ileum close to the ileocecal valve. Histologically, the tumor was diagnosed as moderately to poorly differentiated squamous cell carcinoma without components of adenocarcinoma. Therefore, we diagnosed primary squamous cell carcinoma of the ileum. To the best of our knowledge, only 7 other cases of primary squamous cell carcinoma of the small intestine have been reported to date.