2023 Volume 56 Issue 11 Pages 615-621
A 68-year-old man was admitted to another hospital due to abdominal pain. The patient was transferred to our hospital with suspected intussusception based on ultrasound showing a target sign. A tumor was not detected in endoscopic screening, but enhanced CT and abdominal ultrasound showed a 4-cm tumor near the ileum and swelling of regional lymph nodes. Laparotomy revealed the tumor and the swollen lymph nodes located approximately 50 cm proximal to the terminal ileum. Segmental resection of the ileum with lymph node dissection was performed. The pathological diagnosis was hepatoid carcinoma of the ileum. Serum carbohydrate antigen (CA 19-9) decreased from 1,179 U/ml to 78.6 U/ml at 2 months after surgery. However, portal vein tumor thrombus and recurrence of liver metastasis were detected 4 months after surgery, and the patient died 6 months after surgery. We herein report this case as a rare example of hepatoid carcinoma of small bowel cancer.