2023 Volume 56 Issue 8 Pages 427-435
The patient was a 64-year-old man in whom upper endoscopy revealed a 2-cm gastric submucosal tumor. Endoscopic US suggested a gastrointestinal stromal tumor derived from the fourth layer, but fine-needle aspiration failed to diagnose the tumor, so laparoscopic resection was performed for diagnostic treatment. The tumor was pedunculated and extragastric, and was resected using an autosuture device. Histopathological examination showed that the tumor was continuous with the muscularis propria and subserosa. Spindle-shaped cells with hyalinized collagen fibers proliferated, and calcification and inflammatory cell infiltration were present. Immunohistochemical staining of the spindle cells was positive for vimentin, but negative for CD34, c-kit, α-smooth muscle actin, desmin, and S-100, and the tumor was diagnosed as a calcifying fibrous tumor. One year after the operation, there has been no recurrence. We report this case as a rare example of a calcifying fibrous tumor originating from the gastric wall.
