1990 Volume 23 Issue 3 Pages 727-731
We studied the correlation between postoperatively administered hemostatics and the incidence of adhesive ileus in 226 patients with gastric cancer, retrospectively. The incidence of adhesive ileus was 14% (20/149) in the menatetrenone-treated group and 3.9% (3/77) in the non-treated group. There was a significant difference between these two groups. In the group in which the patients had been given more than 400 mg of menatetrenone, the incidence of adhesive ileus was 18.8% (6/32), about four times that of the non-administered group. In the patients who had been administered other hemostatics (carbazochrome sodium sulfonate, tranexamic acid, hemocoagulase, conjugated estrogens), adhesive ileus did not occur more frequently than in the patients who had not been given the hemostatics. Prophylactic administration of a large dose of menatetrenone must be avoided, since the incidence of adhesive ileus may be increased by menatetrenone.
