1992 Volume 25 Issue 1 Pages 14-18
We infused physiological saline into the abdominal cavity and performed preoperative peritoneal cytology (PPC) and measurement of CA 125 in the recovered fluid in 54 patients with gastric cancer in whom no peritoneal tumor or ascites was observed by palpation, US, or CT. In the diagnosis of peritoneal dissemination, the sensitivity, specificity and accuracy of PPC were 60%, 95.5% and 88.9%, respectively. These figures were similar to those for peritoneal lavage cytology. The CA 125 level in the recovered fluid correlated well with the serum CA 125 level in P (+) patients. The CA 125 level in the serum did not differ significantly between ps (+) patients and ps (-) patients, but that in the recovered fluid was significantly higher in the ps (+) patients (101.61±0.46 U/ml) than in the ps (-) patients (101.33±0.25 U/ml). No complications of this examination were observed. These results suggest that PPC and measurement of CA 125 in recovered fluid are very useful for preoperatively diagnosing peritoneal dissemination.
