Abstract
Two cases of early gastric cancer with sarcoid reaction in the regional lymph nodes are reported. Case 1: A 54-year-old woman visited a practitioner with the complaint of epigastralgia and was referred to our hospital. A double contrast study revealed a IIc + III lesion on the lesser curvature of the middle body of the stomach and distal subtotal gastrectomy was carried out. Histologically, moderately differentiated tubular adenocarcinoma was found in the submucosal layer. Sarcoid reaction comprised of epithelioid cells and giant cells was seen in regional lymph nodes (15/21). Case 2: A 38-year-old woman with the complaint of fever visited our hospital for further examination. Endoscopy revealed a IIc lesion on the greater curvature of the middle body of the stomach and distal subtotal gastrectomy was carried out. Histologically, papillotubular adenocarcinoma was found in the submucosal layer. Sarcoid reaction was seen in regional lymph nodes (21/39). Only 12 cases of early gastric cancer with sarcoid reaction in the regional lymph nodes have been reported in our country, and we discussed their clinicopathological characteristics.
