Abstract
Primary low grade malignant histiocytoma of the spleen is extremely rare. We report here a case a of 29-yearold man admitted with the complaint of abdominal discomfort. Blood tests revealed anemia, thrombocytopenia, hypoproteinemia and hypoglobulinemia. With a diagnosis of primary malignant lymphoma, a splenectomy was performed and the peritoneum was partially resected because the tumor was adherent to it. The histological diangosis was primary low grade malignant histiocytoma of the spleen. Soon after splenectomy, the anemia, thrombocytopenia, hypoproteinemia and hypoglobulinemia had improved, and the patient is alive and doing well one year after the operation with no signs of recurrence.