Abstract
A case of quadruple cancer including breast, uterine, colon and gastric cancer during a period of 16 years is reported. The 64-year-old woman patient had a family history in which all but one brother had suffered from cancer. She had undergone mastectomy at age 48 due to breast cancer, and total hysterectomy at age 54 due to uterine cancer. She complained of epigastral discomfort, and visited our hospital, where she received a curative operation for colon and gastric cancer (synchronous double cancer). We review a total of 16 cases of quadruple cancer in Japan, 7 (43.8%) of which could be resected. The most common sites were the stomach and colon. The first cancer tended to have a favorable prognosis. It is important to provide follow-up, taking care not only of recurrence but of additional carcinoma.