Abstract
We report two cases of liver metastasis from gastric leiomyosarcoma with long-term survival. In case 1 the patient was a 70-year-old man who was diagnosed as having liver metastasis from gastric leiomyosarcoma 1 year and 7 months after proximal gastrectomy. Partial resection of liver metastases and adjuvant chemotherapy via the portal vein was performede. The patient had survived 3 years and 5 months after the liver resection without recurrence. In case 2 the patient was a 51-year-old man who was diagnosed as having liver metastasis from gastric leiomyosarcoma 2 years and 8 months after total residual gastrectomy. Transcatheter arterial embolization (TAE) was performed three times without reduction of the liver metastases. The patienthas survived 4 years and 10 months after diagnosis of liver metastasis. Although the prognosis for patients with liver metastasis from gastric leiomyosarcoma is poor, both of these patients have survived for a long time. The mean survival period for 16 patients in the Japanese literature after resection of liver metastases from gastric leiomyosarcoma is 19.1 months, and 5 patients survived over 2 years. We suggest that resection of liver metastases from gastric leiomyosarcoma be performed when it is indicated, and when it is not, that TAE be performed many times to achieve long survival.