1993 Volume 26 Issue 7 Pages 1951-1956
The influence of cancer infiltration at the resection margin (infilt (+)) on prognosis for 683 patients who underwent non-curative gastric resection from 1965 to 1984 was studied. The three-year survival rates (3YSR) were evaluated statistically. 3YSR of aw (+) and ow (+) were 40.6% and 36.0%. 3YSR were 32.8% in patients with a single factor of N>R relatively non-curative resection and 10.0% in patients with two factors of N>R relatively noncurative resection plus infilt (+) (p=0.0001). In N>R absolutely non-curative resection, 3YSR of N>R alone was 12.8% and that of N>R plus inilt (+) was 4.8% (not significant, NS). In S3, 3YSR of S3 alone and S3 plus infilt (+) were 28.6% and 0% (NS). 3YSR were 27.8% and 6.3% in patients having the single factor of P1 and P2-3 alone, and 21.4% and 0% in patients with the factors of P1 and P2-3 plus infilt (+) (NS). 3YSR were 5.7% in patients with more than two non-curative factors alone and 3.4% in patients with more than two factors plus infilt (+). From these results, it was concluded that the prognosis for the patients having positive infiltration at the resected margin was not wrong in those with a large tumor burden.